Disease-stage-specific immunometabolic remodeling in pediatric obstructive sleep apnea: a single-cell transcriptomic atlas of adenoid tissue.
EMBO molecular medicine
Yang Q, Cui Y, Huang X, Liu J, Ma X, Gao GF, Pan H, Qin S.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2026
Immunology
Microbiology
Single-Cell Analysis
No items found.
Key Finding
Analysis revealed compromised T-cell and B-cell immunity, as well as reduced antigen processing by innate immune cells, coupled with diminished cell-cell communication in severe OSA group. T-cell receptor and B-cell receptor sequencing also support more infection imprints and abnormal germinal centers and antibody class switching.
Countstar Connection
The study obtained cell-count and viability measurements from the study's cell samples with Countstar Rigel S2 before single-cell analysis in the 2026 EMBO molecular medicine study.
