SCIENTIFIC EVIDENCE

Discovery and characterization of SARS-CoV-2 reactive and neutralizing antibodies from humanized CAMouse HG mice through rapid hybridoma screening and high-throughput single-cell V(D)J sequencing.

Frontiers in immunology

Yang X, Chi H, Wu M, Wang Z, Lang Q, Han Q, Wang X, Liu X, Li Y, Wang X, Huang N, Bi J, Liang H, Gao Y, Zhao Y, Feng N, Yang S, Wang T, Xia X, Ge L.

Publication Overview

Key findings, Countstar context, and access to the original paper.

2022

Single-Cell Analysis

No items found.

Key Finding

A rather obvious preferential usage of IGHV6-1 family was found in these hybridoma clones derived from CAMouse HG mice, which was significantly different from the antibodies found in patients with COVID-19.

Countstar Connection

For the study's cell samples, researchers obtained cell-count measurements with Countstar (model not specified) before single-cell analysis for the study's single-cell analysis.

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