SCIENTIFIC EVIDENCE

Diosmetin Inhibits NETs Formation in Neutrophils Through Regulating Nrf2 Signaling.

Thoracic cancer
Guo L, Luo H, Lei Y, Gu L, Wang Y, Wang S, Lian Z, Li Y, Xiang Y, Du G, Shao R, Tian X, Zhang H, Shen L, Chen J, Wang Y, Huang N, Niu X, Li J.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2025
Immunology
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Key Finding
Then, molecular mechanisms analysis suggested that Nrf2 might be the primary target of diosmetin. Diosmetin exerts as anti-NETs effect through Nrf2 signaling in neutrophils, showing the therapeutic potential in thromboembolism and related pathological processes, such as CAT.
Countstar Connection
Migrated or invaded cell numbers were measured in neutrophil samples with Countstar (model not specified) during migration assessment in the 2025 Thoracic cancer study.
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