Dihydroartemisinin Alleviates the Symptoms of a Mouse Model of Systemic Lupus Erythematosus Through Regulating Splenic T/B-Cell Heterogeneity.
Current issues in molecular biology
Qin H, Zhu X, Liu X, Wang Y, Liang J, Wu H, Wu J.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Immunology
Single-Cell Analysis
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Key Finding
DHA may inhibit B-cell differentiation into plasma cells by modulating effector CD4+ T cells, potentially through the regulation of HIF1α and ligand-receptor interactions, enhancing the study's understanding of DHA's mechanisms in SLE treatment.
Countstar Connection
Countstar (model not specified) measured cell number and viability in the study's cell samples before single-cell analysis in the 2025 Current issues in molecular biology study.