SCIENTIFIC EVIDENCE

Development of Apical-Out Human Fallopian Tube Organoids for Modeling Sperm-Epithelium Interactions

Biology of Reproduction

Chuncheng Lu, Liangdi Su, Zhao Wu, Hongbin Gao, Zhigang Yao, Youzhe Tan, Ao Zhang, Zhuo Wang, Jikun Liu, Wenjie Lai, Hui Zhao

Publication Overview

Key findings, Countstar context, and access to the original paper.

2026

3D Culture

Organoid Culture

Castor S

Key Finding

This study established an apical-out human fallopian tube organoid model for direct sperm–epithelium interaction and showed that sperm DNA integrity drives distinct epithelial responses.

Countstar Connection

Countstar Castor S was used to assess cell concentration and viability during establishment and characterization of the apical-out fallopian tube organoid model.

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