SCIENTIFIC EVIDENCE

Determining M2 macrophages content for the anti-tumor effects of metal-organic framework-encapsulated pazopanib nanoparticles in breast cancer.

Journal of nanobiotechnology
Xu Z, Zhou Z, Yang X, Thakur A, Han N, Li HT, Li LG, Hu J, Li TF, Yan Y.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2024
Cancer Research
Immunology
Single-Cell Analysis
No items found.
Key Finding
High-throughput single-cell RNA sequencing (scRNAseq) revealed that PAZ@Fe-MOF significantly reduced pro-tumorigenic M2-like macrophage populations at tumor sites and suppressed M2-type signaling pathways, such as ATF6-TGFBR1-SMAD3, as well as chemokines including CCL17, CCL22, and CCL24.
Countstar Connection
Countstar (model not specified) supplied cell-viability measurements for the study's cell samples before single-cell analysis in the 2024 Journal of nanobiotechnology study.
View paper ↗
Stay Connected toCountstar Science
Get new publications, application notes, cell analysis insights, and Countstar updates delivered to your inbox.
Meet us online
Products
About Us
Contact
© 2026 Countstar. All rights reserved.