Deglycosylated Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1 Signaling Pathway.
Molecules (Basel, Switzerland)
Ruan H, Gao S, Li S, Luan J, Jiang Q, Li X, Yin H, Zhou H, Yang C.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2021
Immunology
No items found.
Key Finding
In vivo experiments showed that Deg-AZM could significantly reduce bleomycin-induced pulmonary fibrosis and restore respiratory function. The findings show that Deg-AZM exerts antifibrotic effects by inhibiting TGF-β1-induced myofibroblast activation and EMT.
Countstar Connection
Researchers assessed cell numbers in the study's cell samples using Countstar (model not specified) during quality assessment for the reported research.
