Deficiency of Aging-Related Gene Chitinase-Like 4 Impairs Olfactory Epithelium Homeostasis.
Cell proliferation
Wu T, Li W, Zhuang L, Liu J, Wang P, Gu Y, Liu Y, Yu Y.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Single-Cell Analysis
No items found.
Key Finding
Chil4 downregulation in aged organoids reduced the number of mature sensory neurons, suggesting a necessary role of Chil4 in maintaining neuronal generation in the aged OE. Collectively, these observations reveal a previously unidentified function of Chil4, establishing the cellular mechanism underlying OE homeostasis.
Countstar Connection
Researchers relied on Countstar (model not specified) for cell-count and viability measurements in cell suspensions during preparation for single-cell or single-nucleus analysis.
