SCIENTIFIC EVIDENCE

Deciphering the Multifaceted Immune Landscape of Unresectable Primary Liver Cancer to Predict Immunotherapy Response.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Xue J, Yang S, Zhang SS, Fan J, Wu ZL, Sui CJ, Yang YQ, Zhang JF, Liu P, Zhang DJ, Qiu XY, Zhang T, Chen L, Wu G, Wang HY, Tang J.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2024
Cancer Research
Immunology
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Key Finding
CMs decrease more in responders PBMCs, while HLA-DR + CD8 + T cells conformably amplify after ICI-exposure. Responders demonstrate much higher enrichment of B cells or tertiary lymphoid structures in tumor compared to non-responders.
Countstar Connection
Researchers used a Countstar instrument to assess cell numbers in PBMC suspensions during quality assessment in the 2024 Advanced science study.
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