SCIENTIFIC EVIDENCE

Cxcl9 high macrophages recruit circulating Cxcr3+ plasmablasts into kidneys to promote pathogenesis of lupus nephritis mice.

Communications biology
Zhao J, Bai X, Zhou C, Ouyang Q, Zhang Y, Zhang X, Zheng X, Li C, Shen W, Li Q, Cai G, Chen X, Li P, Bai XY.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2025
Immunology
Microbiology
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Key Finding
Based on these findings, this study suggests that Cxcl9 high macrophages are the inducing factor causing the increase of LLPCs in LN kidneys and may be a potential therapeutic target for LN.
Countstar Connection
The researchers assessed cell concentration and viability in the study's cell samples with Countstar Rigel S2 during preparation for single-cell or single-nucleus analysis.
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