Comparative Effects of Umbilical Cord- and Menstrual Blood-Derived MSCs in Repairing Acute Lung Injury.
Stem cells international
Ren H, Zhang Q, Wang J, Pan R.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2018
Bioprocessing
Immunology
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Key Finding
Furthermore, the authors found that UCMSCs secreted higher levels of anti-inflammatory cytokines (interleukin-10 and keratinocyte growth factor) in ALI-related conditions, which may be due to the greater therapeutic capacity of UCMSCs compared with MBMSCs. These findings suggest that MSCs protected the lipopolysaccharide-induced ALI model by regulating inflammation, most likely via paracrine factors.
Countstar Connection
Using a Countstar instrument, the study measured cell numbers in neutrophil samples during sample-quality assessment for the reported research.