Cell division cycle associated 5 promotes colorectal cancer progression by activating the ERK signaling pathway.
Oncogenesis
Shen A, Liu L, Chen H, Qi F, Huang Y, Lin J, Sferra TJ, Sankararaman S, Wei L, Chu J, Chen Y, Peng J.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2019
Cancer Research
Microbiology
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Key Finding
CDCA5 knockdown also significantly decreased phosphorylation of ERK1/2 and expression of c-jun. Taken together, these findings suggest a significant role in CRC progression of CRC, likely by activating the ERK signaling pathway.
Countstar Connection
The study obtained cell-count measurements from the study's cell samples with Countstar (model not specified) during quality assessment in the 2019 Oncogenesis study.