CD7 protein plays a crucial role in T cell infiltration in tumors.
Heliyon
Sheng B, Zhang K, Tian S, Ma R, Li Z, Wu H, Wang T, Jiang L, You F, An G, Meng H, Yang L, Liu X.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2023
Cancer Research
Immunology
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Key Finding
Blocking CD7 in normal T cells did not alter the migration and infiltration, but in Jurkat, CCRF-CEM, and KG-1a tumor cell lines, migration and invasion were significantly reduced after blocking CD7.
Countstar Connection
The research used Countstar (model not specified) for migrated- or invaded-cell count assessment in the study's cell samples during migration assessment for the cancer-model experiments.