Cascade-targeted delivery platform enhances antigen cross-presentation and STING activation for durable cellular immunity.

Through systematic screening, the palmitic acid-modified nano-emulsion was identified as the most effective carrier, exhibiting intrinsic self-adjuvant properties and a strong capacity to elicit cellular immune responses. This synergistic mechanism significantly enhances CD8 + T cell responses and promotes durable memory formation, resulting in potent antitumor efficacy in murine models.

The researchers relied on Countstar (model not specified) to measure cell numbers in the study's cell samples during quality assessment for the immune-cell research.