Studies have shown that long-term coffee consumption is significantly inversely associated with the risk of hepatocellular carcinoma (HCC). The authors found that caffeine had protective effects on HCC induced by DEN in rats through inhibition of cyclic adenosine monophosphate-protein kinase A-cAMP-response element binding protein (cAMP-PKA-CREB) signaling.
Countstar Connection
Countstar Mira BF provided the instrument readout for flow-cytometry cell measurements in the study's cell samples during culture monitoring for the cancer-model experiments.