Bifidobacterium bifidum postbiotics prevent Salmonella Pullorum infection in chickens by modulating pyroptosis and enhancing gut health

The researchers evaluated Bifidobacterium bifidum postbiotics against Salmonella Pullorum infection in chickens and intestinal epithelial-cell models. The treatment improved gut-health indicators, reduced pathogen adhesion and inflammatory damage, and modulated pyroptosis-related responses, supporting postbiotics as a potential non-antibiotic strategy for controlling poultry salmonellosis.

A Countstar Mira BF automated cell analyzer counted chicken small-intestinal epithelial cell suspensions so experimental cultures could be prepared at controlled cell densities.