SCIENTIFIC EVIDENCE

Avian GCGR-mediated continuous fat utilization offers perspectives for obesity treatment.

Nature communications

Zhang C, Wang X, Feng C, Zheng H, Leng S, Jiang Y, Sun Q, Li X, Zhang T, Zhang J, Chen H, Lai S, Makalowski W, Brosius J, Shi Y, He Y, Hu P, Sun Q, Deng C.

Publication Overview

Key findings, Countstar context, and access to the original paper.

2025

Cell Counting & Viability

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Key Finding

Avian GCGR or other constitutively active GCGR variants (human GCGR H339R ) expressed in white adipose tissue of male mice with obesity effectively promoted fat mobilization and sustained body weight loss, with decreased food intake partially contributing to the observed weight reduction.

Countstar Connection

For the study's cell samples, researchers obtained nuclei-count measurements with Countstar Rigel S2 during quality assessment for the reported research.

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