Antiviral and immune modulatory activities of STING agonists in a mouse model of persistent hepatitis B virus infection.
PLoS pathogens
Wang Y, Wu S, Li X, Qiao L, Wang H, Yang G, Yan H, Wang K, Jiang JD, Li Y.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Immunology
Microbiology
Single-Cell Analysis
No items found.
Key Finding
The findings imply that diABZI treatment activates a STING-dependent immune response that controls HBV replication in a mouse model of persistent HBV infection and thus establishes a scientific basis for further development of STING agonists as immune therapeutics for the treatment of chronic hepatitis B.
Countstar Connection
The research used Countstar Rigel S2 for cell-count and viability assessment in the study's cell samples before single-cell analysis for the immune-cell research.
