Antitumor and Adjuvant Activity of λ-carrageenan by Stimulating Immune Response in Cancer Immunotherapy.
Scientific reports
Luo M, Shao B, Nie W, Wei XW, Li YL, Wang BL, He ZY, Liang X, Ye TH, Wei YQ.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2015
Cancer Research
Immunology
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Key Finding
In addition, λ-carrageenan could enhance the secretion of IL17A in spleen and significantly increase the level of TNF-α in tumor, most of which was secreted by infiltrating macrophages. Moreover, λ-carrageenan exhibited an efficient adjuvant effect in OVA-based preventative and therapeutic vaccine for cancer treatment, which significantly enhanced the production of anti-OVA antibody.
Countstar Connection
The researchers relied on Countstar (model not specified) to measure cell numbers in cell suspensions during quality assessment for the cancer-model experiments.
