SCIENTIFIC EVIDENCE

Anti-cancer effects of curcumin on lung cancer through the inhibition of EZH2 and NOTCH1.

Oncotarget
Wu GQ, Chai KQ, Zhu XM, Jiang H, Wang X, Xue Q, Zheng AH, Zhou HY, Chen Y, Chen XC, Xiao JY, Ying XH, Wang FW, Rui T, Liao YJ, Xie D, Lu LQ, Huang DS.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2016
Cancer Research
Immunology
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Key Finding
Curcumin decreased the expression of NOTCH1 through the inhibition of EZH2. These observations suggest that curcumin inhibits lung cancer growth and metastasis at least partly through the inhibition of EZH2 and NOTCH1.
Countstar Connection
Countstar (model not specified) generated cell-count measurements for the study's cell samples during growth assessment for the cancer-model experiments.
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