Andrographolide Attenuates NLRP3 Inflammasome Activation and Airway Inflammation in Exacerbation of Chronic Obstructive Pulmonary Disease.
Drug design, development and therapy
Yu Y, Miao TW, Xiao W, Mao B, Du LY, Wang Y, Fu JJ.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2024
Immunology
No items found.
Key Finding
Moreover, AGP administration effectively suppressed the expression of NLRP3, apoptosis associated speck-like protein that contains a CARD (PYCARD), cysteinyl aspartate-specific protease-1 (Caspase-1), IL-1β, and IL-18 at both the genetic and protein levels.
Countstar Connection
The researchers assessed flow-cytometry cell measurements in the study's cell samples with a Countstar instrument during sample-quality assessment.
