An IGF1-expressing endometrial stromal cell population is associated with human decidualization.
BMC biology
Shi JW, Lai ZZ, Yang HL, Zhou WJ, Zhao XY, Xie F, Liu SP, Chen WD, Zhang T, Ye JF, Zhou XY, Li MQ.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2022
Single-Cell Analysis
No items found.
Key Finding
Single-cell analysis identified an IGF1-positive stromal population associated with the initiation of decidualization, IL1B-positive stromal cells linked to gland degeneration and hemostasis, and immune-trophoblast signaling that may promote decidualization. An altered IGF1-positive to IGF1R-positive stromal-cell ratio was observed in unexplained implantation failure.
Countstar Connection
Countstar (model not specified) served as the instrument for cell-viability assessment in the study's cell samples before single-cell analysis in the 2022 BMC biology study.
