ALG-2 couples T cell activation and apoptosis by regulating proteasome activity and influencing MCL1 stability.
Cell death & disease
He TS, Ji W, Zhang J, Lu J, Liu X.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2020
Immunology
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Key Finding
The study provides support for the notion that T cells are destined for apoptosis after activation, and echoes the previous study about the function of ALG-2 in T cell death.
Countstar Connection
Cell measurements were quantified in the study's cell samples with Countstar (model not specified) during growth assessment for the immune-cell research.