SCIENTIFIC EVIDENCE

Adenosine A2a Receptor Regulates Autophagy Flux and Apoptosis to Alleviate Ischemia-Reperfusion Injury via the cAMP/PKA Signaling Pathway.

Frontiers in cardiovascular medicine
Xia Y, He F, Moukeila Yacouba MB, Zhou H, Li J, Xiong Y, Zhang J, Li H, Wang Y, Ke J.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2022
Immunology
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Key Finding
In vitro model, the authors found that the OGDR-induced autophagosomes and apoptosis caused myocardial cell death, as evidenced by a significant increase in the generation of lactate dehydrogenase and creatine kinase-MB.
Countstar Connection
The researchers measured cell numbers in cell suspensions with Countstar (model not specified) during quality assessment in the 2022 Frontiers in cardiovascular medicine study.
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