Activation of TLR Signaling in Sensitization-Recruited Inflammatory Monocytes Attenuates OVA-Induced Allergic Asthma.
Frontiers in immunology
Huang C, Wang J, Zheng X, Chen Y, Wei H, Sun R, Tian Z.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2018
Immunology
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Key Finding
Finally, the authors found that activation of TLR signaling could increase the expression of T-helper (Th) 1-associated cytokines in inflammatory monocytes. The findings suggest that activation of TLR signaling in sensitization-recruited inflammatory monocytes attenuates OVA-induced allergic asthma by promoting the expression of Th1-associated cytokines.
Countstar Connection
Countstar (model not specified) measured cell numbers in the study's cell samples during quality assessment in the 2018 Frontiers in immunology study.
