A tunable human intestinal organoid system achieves controlled balance between self-renewal and differentiation
Nature Communications
Li Yang, Xulei Wang, Xingyu Zhou, Hongyu Chen, Sentao Song, Liling Deng, Yao Yao, Xiaolei Yin
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
3D Culture
Organoid Culture
Single-Cell Analysis
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Key Finding
This work established a scalable human intestinal organoid culture system that balances stem-cell self-renewal with differentiation and increases cellular diversity under a single culture condition.
Countstar Connection
A Countstar cell counter was used for quality control of organoid-derived single-cell suspensions before 10x Genomics single-cell RNA sequencing.
