A single-cell digital PCR method tailored for quantification of HBV DNA positive cells in liver biopsy tissues.
Journal of translational medicine
Li J, Li H, Zhang X, Liu X, Zhou Z, Wei J, Zhao R, Zhou TC, Zhang Z, Li C.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Single-Cell Analysis
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Key Finding
The proportion of HBV-positive cells offering insights into infection status and identifying patients more likely to achieve a cure. This complements traditional serological markers offering a more nuanced view of CHB infection dynamics and supporting personalized treatment strategies.
Countstar Connection
Single-cell suspensions underwent fluorescence-based cell assessment with Countstar (model not specified) before single-cell analysis in the 2025 Journal of translational medicine study.