SCIENTIFIC EVIDENCE

A recombinant Fasciola gigantica 14-3-3 epsilon protein (rFg14-3-3e) modulates various functions of goat peripheral blood mononuclear cells.

Parasites & vectors

Tian AL, Lu M, Calderón-Mantilla G, Petsalaki E, Dottorini T, Tian X, Wang Y, Huang SY, Hou JL, Li X, Elsheikha HM, Zhu XQ.

Publication Overview

Key findings, Countstar context, and access to the original paper.

2018

Immunology

No items found.

Key Finding

GO enrichment analysis of the interacting proteins identified terms related to apoptosis, protein binding, locomotion, hippo signalling and leukocyte and lymphocyte differentiation, supporting the experimental findings. The data suggest that rFg14-3-3e protein can influence various cellular and immunological functions of goat PBMCs in vitro and may be involved in mediating F. gigantica pathogenesis.

Countstar Connection

Countstar (model not specified) measured migrated or invaded cell numbers in the study's cell samples during the study's migration assessment.

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