A pore-forming protein drives macropinocytosis to facilitate toad water maintaining.
Communications biology
Zhao Z, Shi ZH, Ye CJ, Zhang Y.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2022
Cell Counting & Viability
No items found.
Key Finding
Deletion of toad skin secretions, in which βγ-CAT is a major component, increased animal mortality under hypertonic stress. βγ-CAT was constitutively expressed in toad osmoregulatory organs, which was inducible under the variation of osmotic conditions. During extracellular hyperosmosis, βγ-CAT stimulated macropinocytosis to facilitate water import and enhanced exosomes release, which simultaneously regulated aquaporins distribution.
Countstar Connection
The study used Countstar (model not specified) for cell-concentration, viability, and size assessment in the study's cell samples during quality assessment in the 2022 Communications biology study.
