Zhang LZ, Yang JE, Luo YW, Liu FT, Yuan YF, Zhuang SM.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2020
Cancer Research
No items found.
Key Finding
These findings identify a novel p53/lnc-Ip53 negative feedback loop in cells and indicate that abnormal upregulation of lnc-Ip53 represents an important mechanism to inhibit p53 acetylation/activity and thereby promote tumor growth and chemoresistance, which may be exploited for anticancer therapy.
Countstar Connection
Countstar (model not specified) measured cell numbers in the study's cell samples during growth assessment for the cancer-model experiments.
