A new strategy in bioreactor scale-up and process transfer using a dynamic initial vvm according to different aeration pore size.

At the same time, the $100 billion market is distributed among more than 200 listed drugs, which indicates that the production demand for monoclonal antibody drugs is diverse. The showed a quantitative relationship between the aeration pore size and the initial aeration vvm in the P/V range of 20 ± 5 W/m 3.

The research obtained cell-count measurements from the study's cell samples using a Countstar instrument during quality assessment for the reported research.