SCIENTIFIC EVIDENCE

A drug screening to identify novel combinatorial strategies for boosting cancer immunotherapy efficacy.

Journal of translational medicine
Zhang Z, Wang G, Zhong K, Chen Y, Yang N, Lu Q, Yuan B, Wang Z, Li H, Guo L, Zhang R, Wu Z, Zheng M, Zhao S, Tang X, Shao B, Tong A.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2023
Cancer Research
Immunology
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Key Finding
Mechanistically, JK184 enhances B7-H3 CAR T cells infiltrating in xenograft mouse models. These data show that JK184 may be a potential adjutant in combination with CAR T cells or ICB therapy.
Countstar Connection
Countstar Rigel S5 supported assessment of cell numbers in T-cell samples during growth assessment in the 2023 Journal of translational medicine study.
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