SCIENTIFIC EVIDENCE

A Chinese Prescription Yu-Ping-Feng-San Administered in Remission Restores Bronchial Epithelial Barrier to Inhibit House Dust Mite-Induced Asthma Recurrence.

Frontiers in pharmacology
Bao K, Yuan W, Zhou Y, Chen Y, Yu X, Wang X, Jia Z, Yu X, Wang X, Yao L, Wang S, Xu Y, Zhang Y, Zheng J, Hong M.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2019
Bioprocessing
Immunology
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Key Finding
In vitro, DSG1 interference ed in increased thymic stromal lymphopoietin (TSLP) secretion, and epithelial barrier compromise evidenced by significantly elevated transepithelial electrical resistance (TEER) and increased 4-kDa FITC-dextran influx. The data not only demonstrated the pivotal role of DSG1 in asthma pathogenesis, but also provided a novel and potent therapeutic strategy against chronic asthma.
Countstar Connection
Countstar (model not specified) served as the instrument for cell-count assessment in the study's cell samples during quality assessment in the 2019 Frontiers in pharmacology study.
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