Trends Immunol: Shi yufang and some other researchers revealed the action mechanism of mesenchymal s
Recently, by the international famous magazine Cell Press the Trends of Immunology in magazine asked, life sciences, Chinese academy of sciences, Shanghai institute/institute of Shanghai jiaotong university school of medicine, health science jade matter researchers led by immunization and tissue stem cells research published online in January 2012, the topic "How mesenchymal stem cells interact with tissue immune responses" research review articles.
This review is based on jade matter research group in recent years for immunology of mesenchymal stem cells between the main research results and the latest progress in the field, system elaborated the mesenchymal stem cells interact with the immune system and its mechanism, the role of the disease process, and the effects on wound healing and its broad prospects in clinical application, put forward the need to solve the key problems in this field.
MACs is another kind of tissue stem cell except hematopoietic stem cell in bone marrow, which is usually widely distributed in bone marrow, liver, fat, umbilical cord and some parts. Therefore, mesenchymal stem cell transplantation has a broad application prospect in the field of regenerative medicine. Meanwhile, as an important immunomodulatory cell, MSCs has a strong regulatory effect on the immune system after the stimulation of inflammatory cytokines, so MSCs is expected to be applied in the treatment of systemic lupus erythematosus and other autoimmune diseases. In jade role when the researchers, led by the team ectomesenchymal stem cell researchers for interacting with the immune system, the research work of the system is clarified the mesenchymal stem cells for the regulation of the immune system to the specific mechanism, greatly enriched people's understanding of ectomesenchymal stem cells for, remarkable achievements in the research field, received extensive attention of the international counterparts.
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