There’s new advances in the study of schizophrenia susceptibility genes
Schizophrenia is a kind of complex mental disease regulated by multiple genes. It is a kind of most common mental disease characterized by the division of basic personality, thinking, emotion and behavior and the incoordination between mental activity and environment. It often occurs in young and middle-aged people and then affects behavior and emotion. With the development of research methods and the increase of sample size, many new schizophrenia susceptibility genes have been found.
According to Li Ming, a doctoral candidate at the kunming institute of animal sciences' sabine laboratory, CMYA5 has recently been identified as a new schizophrenia susceptibility gene by the university of Virginia in European and African populations in the United States.
To explore wether CMYA5 in China is the susceptibility genes of schizophrenia in the population or not, Li Ming and researchers from the Chinese academy of medical sciences institute of basic medical, psychiatric hospital in yunnan province, such as yuxi city second people's hospital and the university of Virginia unit cooperation, for Beijing, China and yunnan region 5605 case-control samples to the genetic analysis of the system.
Study found that people in Europe CMYA5 in a significantly associated with schizophrenia, the sequence of polymorphic loci is not associated with schizophrenia, and the other one in Europe caused wide public concern over the site of the crowd were significantly associated with schizophrenia, confirmed CMYA5 in China is also a susceptibility genes of schizophrenia in the crowd.
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