The study used stem cells from laboratory mice to grow into pituitary glands
A study published online November 9 in the British journal Nature says, Japanese researchers created a pituitary gland from embryonic stem cells in laboratory mice, and the resulting pituitary was able to produce hormones normally when transplanted into mice with a defective pituitary gland. This suggests that doctors may be able to treat related human diseases in this way.
Pituitary gland is an endocrine organ located in the lower part of the brain, which secretes a variety of hormones. It grows and develops in the body, regulate blood pressure, female milk secretion and other aspects have played an important role. It's a very complicated organ and it's not easy to treat if it's impaired.
Researchers at the riken center for developmental biology and other institutions in Japan reported that they used embryonic stem cells from laboratory mice to grow into pituitary glands in a special three-dimensional culture. Embryonic stem cells (escs) are cells that exist in human and many animal embryos and have the potential to differentiate into various organs and tissues.
The study showed that in mice with a defective pituitary gland and decreased levels of the hormone, levels rose when the pituitary was implanted. This shows that the cultured pituitary gland has the normal function of secreting hormones.
The next step, the researchers say, is to try to grow a human pituitary gland. They hope to be able to do this in three years. But because there are more questions to be considered for human pituitary transplants, it will take longer to actually treat the disease by transplanting a cultivated pituitary.
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