Novel Lysosomal-Associated Transmembrane Protein 4B-Positive Stem-Like Cell Subpopulation Characterizes High-Risk Colorectal Cancer Subtypes.
MedComm
Fang Y, Fu T, Xiong Z, Zhang Q, Liu W, Yu K, Le A.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Cancer Research
No items found.
Key Finding
Stratification by LAPTM4B-positive and LGR5-positive stem-like cell ratios defined four colorectal cancer stem-like subtypes. The LAPTM4B-dominant CSS2 subtype was associated with the poorest prognosis, with a reported hazard ratio of 2.31.
Countstar Connection
Within the study, Countstar Rigel S2 measured cell concentration and viability in the study's cell samples during preparation for single-cell or single-nucleus analysis.
