Found the protein regulation mechanism that interferes with the growth and movement of cancer cells
A team of researchers at home and abroad has identified, at the molecular level for the first time in the world, the mechanism of motion protein regulation that interferes with the formation of tetrapod, a growth cone, after inducing nerve and cancer cell migration, said park jun-tak, President of the Korea institute for basic science support (kase).
The results of this study will help to understand cell growth and proliferation in the new vision, and the prospect will provide the basic information necessary for the development of substances that impede the proliferation of cancer cells.
This study is the result of a joint international study conducted by Dr. Hyun seok cheng group of basic research and professor ikebe michio group of medical college of Massachusetts state university.
Tetrapod is a thin, transparent pseudopod that is found in most cell bodies. The formation of this pseudopod not only interferes with the movement of nerves and cancer cells, but also plays an important role in the physiological recovery process, blood vessel growth, and the signaling system between cells similar to wound treatment.
Although much work has been done recently on the major motor proteins that regulate the formation of tetrapod, it is only in the early stages of identifying the molecular level of the regulatory principle, and the development of the basic disease treatment system based on the active inhibition principle has been completely stateless.
Basis, head of research explained for this: "this study in determining movement protein inside the protein of inactive, the combination of the relationship between the use of the original molecular biology technique and single particle analysis of electron microscope technology, through the analysis of the fusion at the molecular level in the world is first find out the significance of the study".
Dr Jeong said: "the fact that the structural changes of functional proteins in biomechanics are closely related to the functional changes of cells is illustrated by the molecular structure of vision. In the future, we will continue to carry out the high-imaging fusion Imaging study to find the correlation between the inhibition of cancer cell growth and the regulatory principles of motion proteins ".
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