Embryonic Stem Cells for Bleeding Tubes in Israel
In collaboration with scientists from Rapport Medical College of Haifa Polytechnic University and Haifa Rambam Medical Center, Israel, new blood vessels have been developed for the first time using recoded embryonic stem cells, which are of great significance in the treatment of vascular damage caused by stroke and heart disease.
Researchers are said to have used biotechnology to produce a large number of therapeutically available peridermal cells in the laboratory, which are important components in the formation of blood vessels. During the differentiation of embryonic stem cells, they used biometric markers of cell membranes to produce these normal functional peridermal cells.
When they injected these cells into the leg muscles of experimental rats, which were almost completely blocked by blood vessels, they not only formed new blood vessels, but also restored the function of muscle cells damaged by the lack of normal oxygen supply.
Professor Josephine Iskovich, who led the study, said that the peridermal cells they developed were derived from embryonic and adult stem cells donated to medical research. Adult stem cells can be extracted from patients and re-coded by genetic engineering technology, which can make them have the characteristics of embryonic stem cells and differentiate into the required somatic cells. Because adult stem cells come from the patient itself, the peridermal cells produced will not be rejected by the patient's immune system.
Researchers said that although the technology is far from practical application, it is an important breakthrough with many aspects, which will help people to deepen understanding of the process of vascular growth and develop new methods to treat vascular damage caused by blockage.
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