Do research to use stem cells from laboratory mice to grow pituitary glands
In a study published online on November 11th in the British journal Nature, researchers in Japan created a pituitary gland from embryonic stem cells in laboratory mice, and the cultivated pituitary gland was able to produce hormones normally after being transplanted into mice with a defective pituitary gland. This suggests that doctors may be able to cure human diseases in this way.
Pituitary gland is an endocrine organ located in the lower part of the brain, which secretes a variety of hormones and plays an important role in many aspects such as body growth and development, regulation of blood pressure, and female milk secretion. It's a very complicated organ and it's not easy to cure if it's impaired.
Researchers at the riken center for developmental biology and other institutions in Japan reported that they used embryonic stem cells from laboratory mice and cultured them into pituitary glands in a special three-dimensional environment. Embryonic stem cells (es cells) are cells that exist in human and many animal embryos and have the potential to differentiate into various organs and tissues.
The study showed that in mice with a defective pituitary gland and decreased levels of the hormone, levels rose when the pituitary was implanted. This shows that the cultured pituitary gland has the normal function of secreting hormones.
The researchers said they would try to cultivate a human pituitary gland and hope to be able to do so in three years, but it would take longer to actually treat the disease by transplanting an artificial pituitary because there are more questions to consider.
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